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- Challenges and Chances: A Review of the 1st Stem Cell Community Day
- Summertime, and the Livin’ Is Easy…
- Follow-on-Biologics – More than Simple Generics
- Bacteria Versus Body Cells: A 1:1 Tie
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- They Are Invisible, Sneaky and Disgusting – But Today It’s Their Special Day!
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- What You Need to Know about Antibiotic Resistance – Findings, Facts and Good Intentions
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- From Research to Commerce
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- Taskforce Microbots: Targeted Treatment from Inside the Body
- Eyes on Cancer Therapy
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- Challenges and Chances: A Review of the 1st Stem Cell Community Day
- Summertime, and the Livin’ Is Easy…
- Follow-on-Biologics – More than Simple Generics
- Bacteria Versus Body Cells: A 1:1 Tie
- Behind the Crime Scene: How Biological Traces Can Help to Convict Offenders
- Every 3 Seconds Someone in the World Is Affected by Alzheimer's
- HIV – It’s Still Not Under Control…
- How Many Will Be Convicted This Time?
- Malaria – the Battle is Not Lost
- Physicians on Standby: The Annual Flu Season Can Be Serious
- At the Forefront in Fighting Cancer
- Molecular Motors: Think Small and yet Smaller Again…
- Liquid Biopsy: Novel Methods May Ease Cancer Detection and Therapy
- They Are Invisible, Sneaky and Disgusting – But Today It’s Their Special Day!
- How Many Cells Are in Your Body? Probably More Than You Think!
- What You Need to Know about Antibiotic Resistance – Findings, Facts and Good Intentions
- Why Do Old Men Have Big Ears?
- The Condemned Live Longer: A Potential Paradigm Shift in Genetics
- From Research to Commerce
- Chronobiology – How the Cold Seasons Influence Our Biorhythms
- Taskforce Microbots: Targeted Treatment from Inside the Body
- Eyes on Cancer Therapy
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JP | JPY
BioFlo® 320
The Smarter Solution
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製品情報
The BioFlo 320 is a universal controller for bioprocessing at bench scale. It is suitable for cell culture as well as fermentation applications and can be used with glass and BioBLU® Single-Use Bioreactors. Powerful technology for precise process monitoring and control, a large working volume range, and software features that save time and reduce risks make it a reliable partner for developing robust processes and moving them from R&D to production.追加でダウンロードできる材料がありますこのページの最後に
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製品情報
アプリケーション
特徴
製品情報
The BioFlo 320 is highly configurable to suit your requirements
The BioFlo 320 offers the highest level of application flexibility, made possible by features like universal connections for analog and digital sensors, up to six integrated pumps, a highly configurable gas flow control, and compatibility with a wide range of glass and single-use bioreactors.
• Suitable for the cultivation of human and animal cells, including stem cells, as well as microbial fermentation.
• Supports batch, fed-batch, continuous, and perfusion mode.
• Suitable for many applications, including the production of cells, secreted proteins, viral vectors, plasmids, and small molecules.
The BioFlo 320 seamlessly connects R&D to production
The BioFlo 320 is compatible with a wide selection of glass and single-use bioreactors, providing working volumes from 400 mL to 40 L on a single platform. In combination with the BioFlo 720 bioreactor control system, the BioFlo platform supports one of the widest range of single-use solutions, allowing the scale-up of your process to up to 2,000 L.
• Integrated Scale Up Assist software feature simplifies the calculation of important process parameters necessary to scale up and down.
• Validation packages are available for GMP-regulated processes.
• Emerson® DeltaV integration with the BioFlo 320 simplifies tech-transfer, scale-up, and recipe sharing.
Integrated software assistants save time and mitigate risks
Monitoring the controller and the process is key to successful process development. The BioFlo 320 software is designed to provide you with the status of both.
• Alarm functions automatically inform about the status of the process.
• The diagnostic screen provides information on the hardware status and upcoming maintenance.
• Auto Calibrate – automatic calibration of all connected DO sensors at once reduce preparation time and ensures consistency.
The BioFlo 320 offers the highest level of application flexibility, made possible by features like universal connections for analog and digital sensors, up to six integrated pumps, a highly configurable gas flow control, and compatibility with a wide range of glass and single-use bioreactors.
• Suitable for the cultivation of human and animal cells, including stem cells, as well as microbial fermentation.
• Supports batch, fed-batch, continuous, and perfusion mode.
• Suitable for many applications, including the production of cells, secreted proteins, viral vectors, plasmids, and small molecules.
The BioFlo 320 seamlessly connects R&D to production
The BioFlo 320 is compatible with a wide selection of glass and single-use bioreactors, providing working volumes from 400 mL to 40 L on a single platform. In combination with the BioFlo 720 bioreactor control system, the BioFlo platform supports one of the widest range of single-use solutions, allowing the scale-up of your process to up to 2,000 L.
• Integrated Scale Up Assist software feature simplifies the calculation of important process parameters necessary to scale up and down.
• Validation packages are available for GMP-regulated processes.
• Emerson® DeltaV integration with the BioFlo 320 simplifies tech-transfer, scale-up, and recipe sharing.
Integrated software assistants save time and mitigate risks
Monitoring the controller and the process is key to successful process development. The BioFlo 320 software is designed to provide you with the status of both.
• Alarm functions automatically inform about the status of the process.
• The diagnostic screen provides information on the hardware status and upcoming maintenance.
• Auto Calibrate – automatic calibration of all connected DO sensors at once reduce preparation time and ensures consistency.
Intelligent Sensors
• Integrated Mettler Toledo Intelligent Sensor Management (ISM) platform
• Universal connections for up to four analog or digital (ISM) sensors
• pH: analog or digital (ISM)
• DO: analog or digital (ISM)
• Optical DO: digital (ISM)
• Redox: analog or digital (ISM)
• CO2: digital (ISM)
• Real-time sensor diagnostics anticipate sensor failure
Advanced Software Solutions
• Control eight units from a single user interface
• Automatic gas mixing algorithms for simplified control (4-gas, 3-gas)
• O2 enrichment, N2 enrichment
• Ten-point cascade feature for sophisticated control strategies
• Built-in elapsed fermentation timer for batch management
• Trend display with up to twelve process values within a single view
• Remote access via PC or tablet
Small footprint
From R&D laboratories to pilot-scale production facilities, space is an important factor when selecting the right equipment. The BioFlo 320 offers flexibility, better control, and maximum functionality while occupying a fraction of the valuable lab space of similar systems. This means greater efficiency and productivity at a lower operating cost for your lab.
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アプリケーション
- Universal bench-scale controller for cell culture and fermentation applications
- Fermentation of aerobic and anaerobic bacteria, yeasts, and fungi
- Cultivation of mammalian, insect, and human cell lines
- Cultivation of stem cells
- Specialized packed-bed impeller for the cultivation of anchorage and non-anchorage dependent cells, for example for vaccine process development
- Cell culture on microcarriers using specialized cell-lift impeller
- Suitable for batch, fed-batch, and continuous/perfusion processes
特徴
- Universal control for both microbial and cell culture applications
- Controls up to eight systems from a single user interface
- Interchangeable autoclavable and BioBLU Single-Use Bioreactors
- Up to six integrated pumps capable of operating in variable-speed mode
- Integrated Mettler Toledo® ISM® platform
- Built-in optical pH sensing technology for use with the BioBLU Single-Use Bioreactors
- Field-upgradable TMFC drawers for sparge and overlay gas
- Eight independently controlled process gas supplies
- Enhanced software package with new cascade and time profile features
- DeltaV compatibility available through DeltaV Discovery and DeltaV ProPlus PAS
- Validation packages available for GMP-regulated processes
- Compatible with DASware Software Suite or BioCommand for bioprocess information management