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      • BioFlo®/CelliGen® 510
      More Product Details ...
      Catalog no. 0082140293

        • BioFlo®/CelliGen® 510
        More Product Details ...
        Catalog no. 0082140295

          • BioFlo®/CelliGen® 510
          More Product Details ...
          Catalog no. 0082140294

            • Installation Qualification, BioFlo®/CelliGen® 510
            More Product Details ...
            Catalog no. 0082140297

              • Operational Qualification, BioFlo®/CelliGen® 510
              More Product Details ...
              Catalog no. 0082140298

                • Installation Qualification/Operational Qualification, BioFlo®/CelliGen® 510
                More Product Details ...
                Catalog no. 0082140299

                Product Information

                Applications

                Features

                The CelliGen 510 is a compact sterilizable-in-place cell culture system ideal for pilot to small scale production processes. The modular design features a wide variety of standard options allowing this system to be flexible enough to meet most process requirements.


                Gas flow
                • Various combinations of one, two, three or four TMFCs:
                0.06  –   3 SLPM
                0.3  –   15 SLPM
                0.6  –   32 SLPM
                1  –   64 SLPM
                • Air Wash System with TMFC (0  – 15 or 0  –  32 SLPM)
                • Overlay with TMFC (0 –  15 or 0  – 32 SLPM)
                • Overlay (valve only)

                Exhaust line
                • Exhaust condenser
                • Manual or automatic pressure control

                Impellers
                • Rushton-type – Used commonly for robust cell lines such as bacteria, yeasts, and algae, where maximum OTR is desired.
                • Pitched-blade – Commonly used with mammalian, insect or other shear sensitive cell lines for batch, fed-batch or continuous cultures. Produces axial and radial mixing. Provided as standard with the CelliGen 510 bioreactors.
                • Marine – Commonly used with mammalian, insect, or other shear sensitive cell lines for batch, fed-batch or continuous cultures. Produces axial mixing
                • Spinfilter – For suspension or microcarrier cultures where a dip tube inside the filter withdraws cell media as harvest or waste
                • Cell-Lift – Specially designed to provide uniform circulation for both suspension and microcarrier cultures. Can be used with optional decanting columns for perfusion cultures
                • Packed-bed – For secreted products from anchorage-dependent and suspension cells, this impeller immobilizes cells in a bed of Fibra-Cel® Disks to provide extremely high cell densities

                Sensors
                • Single or redundant pH/DO
                • Redox
                • Foam/level

                Addition and sampling
                • Resterilizable sampling valve
                • Resterilizable addition valves (4 max)
                • Resterilizable addition/harvest valve with dip tube (2 max)
                • 1.5 in sanitary fitting 7-port septum
                • Addition vessels (glass/stainless steel)
                • Decanters
                • Sterile sampling assembly

                Documentation packages to support qualification in GMP regulated processes
                • Basic Package
                • Basic Plus Package
                • Enhanced Package

                Utility regulator & pre-filter kits
                • Process air pre-filter/regulator kit
                • Instrument air pre-filter/regulator kit
                • Water pre-filter/regulator kit
                • Process steam regulator kit
                • Utility steam pre-filter/regulator kit
                • Utility connection kit

                Additional options
                • Sprayballs for clean-in-place of vessel
                • External variable-speed pumps
                • External scales
                • Spare parts kits
                • Preventative maintenance kits
                • Mobile table
                • System passivation
                • Glycol/chiller heat exchanger