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    • BioFlo®/CelliGen® 510
    More Product Details ...
    Catalog no. 0082140293

      • BioFlo®/CelliGen® 510
      More Product Details ...
      Catalog no. 0082140294

        • Installation Qualification, BioFlo®/CelliGen® 510
        More Product Details ...
        Catalog no. 0082140297

          • Operational Qualification, BioFlo®/CelliGen® 510
          More Product Details ...
          Catalog no. 0082140298

            • Installation Qualification/Operational Qualification, BioFlo®/CelliGen® 510
            More Product Details ...
            Catalog no. 0082140299

              • BioFlo®/CelliGen® 510
              More Product Details ...
              Catalog no. 0082140295

              Product Information

              Applications

              Features

              The CelliGen 510 is a compact sterilizable-in-place cell culture system ideal for pilot to small scale production processes. The modular design features a wide variety of standard options allowing this system to be flexible enough to meet most process requirements.


              Gas flow
              • Various combinations of one, two, three or four TMFCs:
              0.06  –   3 SLPM
              0.3  –   15 SLPM
              0.6  –   32 SLPM
              1  –   64 SLPM
              • Air Wash System with TMFC (0  – 15 or 0  –  32 SLPM)
              • Overlay with TMFC (0 –  15 or 0  – 32 SLPM)
              • Overlay (valve only)

              Exhaust line
              • Exhaust condenser
              • Manual or automatic pressure control

              Impellers
              • Rushton-type – Used commonly for robust cell lines such as bacteria, yeasts, and algae, where maximum OTR is desired.
              • Pitched-blade – Commonly used with mammalian, insect or other shear sensitive cell lines for batch, fed-batch or continuous cultures. Produces axial and radial mixing. Provided as standard with the CelliGen 510 bioreactors.
              • Marine – Commonly used with mammalian, insect, or other shear sensitive cell lines for batch, fed-batch or continuous cultures. Produces axial mixing
              • Spinfilter – For suspension or microcarrier cultures where a dip tube inside the filter withdraws cell media as harvest or waste
              • Cell-Lift – Specially designed to provide uniform circulation for both suspension and microcarrier cultures. Can be used with optional decanting columns for perfusion cultures
              • Packed-bed – For secreted products from anchorage-dependent and suspension cells, this impeller immobilizes cells in a bed of Fibra-Cel® Disks to provide extremely high cell densities

              Sensors
              • Single or redundant pH/DO
              • Redox
              • Foam/level

              Addition and sampling
              • Resterilizable sampling valve
              • Resterilizable addition valves (4 max)
              • Resterilizable addition/harvest valve with dip tube (2 max)
              • 1.5 in sanitary fitting 7-port septum
              • Addition vessels (glass/stainless steel)
              • Decanters
              • Sterile sampling assembly

              Documentation packages to support qualification in GMP regulated processes
              • Basic Package
              • Basic Plus Package
              • Enhanced Package

              Utility regulator & pre-filter kits
              • Process air pre-filter/regulator kit
              • Instrument air pre-filter/regulator kit
              • Water pre-filter/regulator kit
              • Process steam regulator kit
              • Utility steam pre-filter/regulator kit
              • Utility connection kit

              Additional options
              • Sprayballs for clean-in-place of vessel
              • External variable-speed pumps
              • External scales
              • Spare parts kits
              • Preventative maintenance kits
              • Mobile table
              • System passivation
              • Glycol/chiller heat exchanger