What does the term 2DMix-Control technology describe/stand for?

2DMix-Control technology describes the ability of the MixMate, ThermoMixer C and ThermoMixers F to mix small sample volumes in various plate and tube formats quickly and in a controlled manner. To achieve this, the interplay of all crucial factors for efficient and controlled mixing, have been optimized. And these are: - Generation of sufficient mixing energy: due to an orbital mixing movement at a high mixing speed and a relatively large mixing radius (1.5 mm) the devices generate enough mixing energy (analogous to g-force in centrifuges) to mix even the smallest volumes efficiently. - Minimized loss of mixing energy: special attention was paid to reducing inherent vibration. Smooth operation combined with reliable stability ensures that all the mixing energy is available for mixing and not wasted through transmission of vibrations to the device or its surroundings. - Controlled transmission of energy from the device to the sample: Minimizing vertical movements enable a plane, 2-dimensional (2D) mixing stroke. This, in conjunction with the reliable plate and tube holders and SmartBlocks, prevents uncontrolled chaotic movements and allows all formats to be held securely, even at high mixing frequencies.

Which cleaning and disinfection agents can be recommended for cleaning and disinfection of ThermoMixer C, ThermoMixer F and ThermoStat C?

Switch off the device, disconnect the mains/power plug and make sure that no liquid can get into the inside of the housing. When cleaning has been completed, the device should only be connected when it is fully dry on the inside and on the outside. Use lint-free cloth and soft bottle brush or cotton swabs for SmartBlocks and SmartExtender. Do not use any aggressive chemicals on the device or its accessories such as strong and weak bases, strong acids, acetone, formaldehyde, halogenated hydrocarbons or phenol. If the device is contaminated with aggressive chemicals, clean it immediately using a mild cleaning agent and wipe it off with dist. water afterwards. Recommended cleaning agents: mild, soap-based lab cleaner dist. water Recommended disinfectants: ethanol (70%) isopropanol (70%) Please follow the detailed safety instructions in the Operating Manual.

Is the housing of ThermoMixer C, ThermoMixer F and ThermoStat C stable against UV irradiation?

A disinfection by UV irradiation cannot be recommended, because discoloration of the housing materials can occur.

Which DNA and RNAse deconatmination agents can be recommended for decontamination of the devices and the SmartBlocks?

We tested DNA away and RNase away and we can recommend to use both agents.

How can the temperature accuracy be verified?

The best possible temperature accuracy can be guaranteed by individually adjusting a SmartBlock. Optimized temperature control for each block type keeps temperature overshoots and deviations caused by external interferences to a minimum. To guarantee optimal performance over the entire period of use, Eppendorf offers a preventive maintenance program and certification services: your Eppendorf ThermoMixers, ThermoStat C as well as the SmartBlocks are regularly cleaned, checked and adjusted. Additional information is available at: https://www.eppendorf.com/epservices . Customers can also verify the temperature accuracy by themself. Eppendorf provides for that purpose the Temperature Verification System – Single Well for Eppendorf Mastercyclers (0056 000.003) in combination with the 384 well Sensor (0056 002.006).

Is it possible to run more than one program in automatic succession on a ThermoMixer or ThermoStat C?

No. Each program has to be chosen and run separately. But the 4 possible steps within a program run in automatic succession.

Can PCR plates be used in SmartBlock plates respectively ThermoMixer FP?

SmartBlock plates and ThermoMixer FP (with the fixed SmartBlock plates) are dedicated for using MTP’s, DWP’s and also other skirted plates which meet the SBS standard. For optimal usage of PCR plates the SmartBlock PCR 96 and PCR 384 in combination with ThermoMixer C or ThermoStat C is the proper choice. These SmartBlocks possess conical bores which surround the conical wells of PCR plates properly for a perfect temperature transition.

Please contact your local Eppendorf Service Team. You find the contact data on our homepage or in the information materials.

What is IQ or OQ and what do I need them for?

Installation and operational qualification; the IQ documents that the device has been delivered and installed correctly. The OQ checks the correct functioning of a device. IQ/OQ ensure that your quality management requirements are met and that your device operates properly and in accordance with the manufacturer’s specifications.

What does the temperature verification include and how often does it need to be carried out?

To ensure that your ThermoMixer delivers reproducible and correct results, temperature verification and adjustment - if required - are strongly recommended. Temperature verification is a very accurate and precise method and complies with all laboratory requirements with regard to documentation and detection in accordance with national and international standards.

How can temperature accuracy be verified?

The best temperature accuracy possible is ensured by the individual adjustment of each SmartBlock. The Eppendorf Temperature Verification System- Single Channel is used to check the temperature accuracy of the thermoblock. In combination with the temperature sensor for the Eppendorf ThermoMixer, the exact temperature in the thermoblock can be measured. You can find further information in the corresponding operating manual.

How can my device be cleaned and which cleaning agents and disinfectants can be used for cleaning and disinfection of ThermoMixer C, ThermoMixer F and ThermoStat C?

Switch off the device, disconnect the mains/power plug and make sure that no liquid can get into the inside of the housing. When cleaning has been completed, the device should only be connected when it is fully dry on the inside and on the outside. Do not use any aggressive chemicals on the device or its accessories such as strong and weak bases, strong acids, acetone, formaldehyde, halogenated hydrocarbons or phenol. If the device is contaminated with aggressive chemicals, clean it immediately using a mild cleaning agent. Use a lint-free cloth and a mild, soapy laboratory cleaner and distilled water. Clean the housing and the thermoblock regularly. Please refer to your operating manual for further information - Maintenance chapter

What types of training or online training do you offer to enable me to improve my skills?

Please visit the Eppendorf webpage about the Eppendorf Training Center or contact your local Eppendorf Service for further information and a quotation.

Is it possible to use the Eppendorf Thermomixer for 24 h and at 7 days?

Yes, this is possible. The customer has just to set the time to endless.

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Eppendorf ThermoStat C

Eppendorf SmartBlock removal by pressing the lever (Step 1)

Eppendorf SmartBlock removal by pressing the lever (Step 2)

Eppendorf SmartBlock removal by pressing the lever (Step 3)

Eppendorf ThermoStat C with selection of different Smartblocks

Eppendorf ThermoStat C with Smartblock 5mL_and 5.0 mL vessels

Eppendorf ThermoStat C equipped with ThermoTop for prevention of condensation

Eppendorf ThermoStat C with SmartBlock 15mL

Front view of Eppendorf ThermoStat C with SmartBlock 1.5 mL_and_tubes

Eppendorf ThermoStat C in front view with_Smartblock 5.0 mL and tubes

Eppendorf ThermoStat C with SmartBlock Plates (front view)

Lab scientist is working with Eppendorf_Thermostat C with SmartBlock PCR 384

Plates can be heated and cooled on ThermoStat C

Eppendorf ThermoStat C with SmartBlock PCR 96

Eppendorf ThermoStat C with ThermoTop and DWP on mixer instrument

IEppendorf ThermoStat C with SmartBlock and sample

Eppendorf ThermoStat C with SmartBlock plates_and lid

Front view on Eppendorf ThermoStat C with_SmartBlock_PCR-96

Eppendorf ThermoMixer and MixMate family

Product Information

The ideal device to accurately set and maintain temperatures: The Eppendorf ThermoStat C is for heating and cooling almost any of your lab vessels. For additional condensation prevention of small volumes we recommend the Eppendorf ThermoTop (optional), a heated lid with condens.protect technology.

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Learn more about sustainability at Eppendorf - incl. how to recognize a sustainable thermoblock instrument

You will find additional download material at the bottom of this page

Products (1)

Services (10)

Accessories (20)

VisioNize (2)

1 Products

Eppendorf ThermoStat C

basic device without thermoblock
220 – 240 V/50 – 60 Hz (EU)

More Product Details ...

Catalog no. 5383000019

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Product Information

Technical Data

Applications

Features

Many experiments require fast heating and cooling steps in a very accurate manner. Precise temperature control is achieved for the ThermoStat C by using optimally balanced heating and cooling elements (peltier technology).

Using different vessel formats?

A wide varity of Eppendorf SmartBlocks are available for the Eppendorf ThermoStat C. These thermoblocks offer you a broad flexibility for use of nearly all common vessel and plate formats.

• Fast and simple block exchange due to Eppendorf QuickRelease
• Optimized block design guarantees maximum temperature transfer to the sample
• Individually sensor‐controlled Eppendorf SmartBlocks allow for block‐specific calibration"

Tired of condensation in your tubes?

We combined the Eppendorf ThermoStat with the PCR cycler approach of a heated lid and generated the Eppendorf ThermoTop^®. The outstanding Eppendorf condens.protect technology reliably prevents condensation within the tube lid – sample concentrations are consistent for the incubation time.
In addition, the temperature homogeneity is further improved. Get optimal sample reaction conditions to produce optimal results.

• Efficient and reliable condensation prevention on tube lids for safe sample heating
• Get constant reaction conditions for optimal enzymatic performance within your sample
• Wireless connection with automatic recognition and operation for user-friendly handling

Missing a second temperature for an incubation at 37 °C or 95 °C at your Eppendorf ThermoStat?

The Eppendorf SmartExtender offers a comfortable incubation tool which can easily be used as an add-on to your existing Eppendorf SmartBlocks and the Eppendorf ThermoMixer C/Fx as well as Eppendorf ThermoStat C. Up to 12 vessels (1.5 mL) can be heated up for a higher throughput and higher flexibility in your lab. The independent heating function for the second temperature enables a parallel usage of an Eppendorf SmartBlock and the SmartExtender. The Eppendorf SmartBlock at the center can still be used for heating and cooling.

Annoyed by uncomfortable handling?

Ergonomics is far beyond the »ergonomically designed chair«. Eppendorf started to optimize the laboratory devices regarding ergonomics already in the early 1970s.
In 2003, we started the PhysioCare Concept, focusing on ergonomic liquid handling devices like our pipettes.
Nowadays, the Eppendorf PhysioCare Concept is broaden up to include further laboratory products as a holistic solution to harmonize the workflow in your laboratory with your health and well-being, e.g. for the Eppendorf ThermoStat:
• Eppendorf QuickRelease for easy and fast block exchange
• Insulated SmartBlock for safe gripping / no burning of fingers
• Direct keys for convenient handling
• Small footprint to enable position in direct arm reach at your bench
• Standardized »user-interface concept« for intuitive handling of devices

Further information about the Eppendorf PhysioCare Concept:
www.eppendorf.com/physiocare/

Struggling with paper-based documentation?

The eLabJournal Electronic Lab Notebook offers an intuitive and flexible solution to document research and track research data like workflow processes where the Eppendorf ThermoStat is involved. Improve efficiency when documenting, organizing, searching, and archiving collected data. With the free eLabJournal add-ons, you can extend the functionality of eLabJournal to a fully integrated Laboratory Information Management System.

Start a free 30-day trial!
Visit www.eLabJournal.com

Efficient lab and device management with VisioNize^® Lab Suite

Are you interested in monitoring your lab devices and receiving notifications e.g., for device alarms? A digital, connected lab offers even more.

Gain access to a modular range of digital services and choose what works for your lab. VisioNize Lab Suite offers everything you need as a Lab Manager or Scientist to get started to digitally manage your lab for increased sample security, compliance needs and maintenance management.

Chart your own course to digital lab excellence! Find out more

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Specifications	Eppendorf ThermoStat C

Sample capacity	All common vessels and plate formats from 5 µL to 50 mL
Product type	Temperature Control
Timer	5 s to 99:30 h, continuous
Interfaces	USB interface
Power supply	220 – 240 V, 50 – 60 Hz
Max. power consumption	200 W
Dimensions (W × D × H)	20.6 × 30.4 × 13.6 cm / 8.1 × 11.9 × 5.3 in
Product weight	4.3 kg / 9.7 lb
Temperature range	Min: 30 °C below RT, max: 110 °C (110 °C when using the SmartBlocks 12 mm or cryo)
Temperature range	Min: 30 °C below RT, max: 110 °C (110 °C when using the 12 mm and cryo SmartBlocks)¹⁾
Temperature settings	-10 °C/110 °C (110 °C when using the SmartBlocks 12 mm or cryo)
Temperature accuracy	Max. ±0.5 °C at 20 – 45 °C¹⁾

Eppendorf ThermoMixer^®
Heating rate	Max. 9 °C/min (when using the SmartBlock PCR 384)¹⁾
Cooling rate	Max. 5.0 °C/min between 110 °C and RT¹⁾

1)depending on SmartBlock used

Downloads: Eppendorf ThermoStat C

Brochure

The Value of Mixing

Eppendorf Temperature Control and Mixing Instruments

PDF 2.1MB

English

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Eppendorf ThermoStat C

ThermoStat C Smartblock 1.5mL_+_tubes

Eppendorf SmartBlock Removal (Step 1)

Eppendorf SmartBlock Removal (Step 2)

Eppendorf SmartBlock Removal (Step 3)

ThermoStat C Smartblock selection