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Fibra-Cel® Disks
Product Information
Fibra-Cel disks are a proven support system used to increase yields of suspension and anchorage-dependent cultures. Fibra-Cel is also available for use in disposable bags, shake flasks and other bioreactor systems.You will find additional download material at the bottom of this page
Product Information
Applications
Features
Product Information
Fibra-Cel is a solid support growth matrix for mammalian, animal, and insect cells, used predominantly for production of secreted products such as recombinant proteins and viruses. Fibra-Cel enables sustained long-term periods of high-density growth in perfusion, without danger of clogging; and eliminates the need for cell filtration to separate cells from the end product.
HEK-293 cells grown on Fibra-Cel disk at day 7 of the growth cycle
High-resolution micrograph of a Fibra‑Cel disk indicating the polyester mesh with polypropylene support
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Applications
- Hybridoma: DA4-4, 123A, 127A, GAMMA, 67-9-B
- Anchorage-Dependent: 3T3, COS, Human Osteosarcoma, MRC-5, BHK, VERO, CHO, rCHO-tPA, rCHO - Hep B Surface Antigen, HEK 293, rHEK 293, rC127 - Hep B Surface Antigen, Normal Human Fibroblasts, Stroma, Hepatocytes
- Insect: Tn-368, SF9, rSF9, Hi-5
Features
- Low pressure drop across the bed of Fibra-Cel minimizes the variability and maintains a global viability of cells over the entire bed
- High surface-to-volume ratios increases the total biomass that can be maintained in the bioreactor greatly enhancing production of cellular products
- Entrapped cells are shielded from the turbulence and are less susceptible to shear forces from impeller blades and sparger gas bubbles
- Higher mass transfer of nutrients and oxygen versus standard microcarrier systems
Downloads: Fibra-Cel® Disks
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