SciVario twin - Flexible from head to toe
The SciVario twin keeps you flexible, wherever your research focus will take you in the future. The future-proof systems can adapt to changing requirements and like this reduce future capital investment.
• Run both microbial and cell culture processes without any hardware adaptations.
• Choose from a wide variety of glass and BioBLU Single-Use Bioreactors, with working volumes from 1.25 to 3.8 L for all and up to 40 L for single-use cell culture bioreactors.
• Upgrade the system’s hardware easily.
• Expand its capabilities by integrating the SciVario twin with software and equipment for remote monitoring, advanced process control, automated sampling, and data analysis.
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SciVario® twin
SciVario twin cropped, front, grey lines
SciVario® twin
0.2 – 3.8 L working volume (autoclavable)
0.25 – 40 L working volume (single-use)
0.2 – 3.8 L working volume (autoclavable)
0.25 – 40 L working volume (single-use)
SciVario slogan
SciVario twin cropped, BioBLU 3c, 1
SciVario twin Angled Bench, Microbiology
With the compact design, you can make the most of precious bench space in the lab.
Product Information
The SciVario twin is a bench-scale parallel bioprocess controller capable of operating two bioreactors individually. It is suitable for cell culture and fermentation applications in R&D and can be used with glass and BioBLU® Single-Use Bioreactors. The SciVario twin is a modular system, making it customizable as well as easily upgradable after installation and therefore adaptable to changing requirements.
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Product Information
Technical Data
Applications
Features
Product Information
Stay flexible with the future proof bay drawer concept
• Eight bays can be equipped with different pumps or other modules.
• The system can be initially delivered with custom configurations and easily upgraded with additional modules to support the changing needs in R&D.
• This concept supports you as a user to avoid additional capital investments into instruments to match future requirements.
Individually control two bioreactors in parallel
• With the SciVario twin you can run one bioreactor or two bioreactors in parallel.
• The two bioreactors can be controlled individually in any combination of vessel type and working volume.
• Parallel processing allows for more runs in less time.
Optimize your workspace
• The compact design of the SciVario twin frees up bench space.
• The device can be easily moved for cleaning and servicing.
• You can easily access often used connectors/accessories, as they are placed on the front.
• Cable management guides and a storage system for accessories let you keep your bench clean and tidy.
Stay flexible in your process control
• The SciVario twin can be connected with digital and analog sensors and detects them automatically.
• The SciVario twin allows for optical pH measurement.
• Be flexible in your gassing strategy by choosing between submerged and overlay gassing with four gases with individual wide-range TMFCs.
• Flexibly add liquids with up to eight pumps per bioreactor. A wide pump flow rate enables the precise additions of small volumes as well as bigger additions to larger vessels.
• You can flexibly select the required pumps and exchange them after purchase.
• The SciVario twin is compatible with the Bioprocess Autosampler for automated sampling and bolus addition.
Software: Combine ease of use and high performance
• All critical process parameters such as temperature, gassing, pH, feeding, and others can be controlled and recorded by the base unit.
• An intuitive user interface and guided workflows assist you through your process to avoid errors.
• The integration with DASware® control offers advanced functionality, like the execution of feed profiles and scripts, process automation, and the integration of 3rd party sensors.
• The connection to BioNsight® cloud software enables remote monitoring and advanced data analysis.
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Technical Data
| Specifications | SciVario twin |
|---|
| Power supply | 100 – 240 V, 50/60 Hz |
| Max. power consumption | 1750 W |
| Dimensions (W × D × H) | 30.6 × 34 × 75 cm / 12.0 × 13.4 × 29.5 in |
| Product weight | 43.1 kg |
| Bacteria/Yeast/Fungi | yes |
| Mammalian/Animal | yes |
| Insect | optional |
| Interchangeable Vessels | yes |
| Validatable | no |
| Stem cells | yes |
|
Bioreactors |
|
| Vessels | Glass/single-use vessels |
| Total volume | 1.3 L to 3.8 L for all variants, up to 40 L for single-use cell culture |
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Agitation |
|
| Drive | Direct/magnetic overhead drive |
| Speed ranges | 60 – 1,600 rpm/25 – 1,250 rpm/25 – 1,900 rpm |
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Gassing |
|
| Gas supply | TMFC; overlay and/or sparger |
| Standard gas flow rates | 0.1 – 1,200 sL/h |
| Standard gas mixing | Air, N2, O2 and/or CO2 |
|
Feeding |
|
| Feed lines per vessel | Up to 6 |
| Standard feed rates (depending on tube diameter) | 0.005 – 600 mL/h (small pump), 4.5 – 5,200 mL/h (large pump) |
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Monitoring and Control |
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| Exhaust condensation | Liquid-free (Peltier) or water-based |
Applications
- Universal bench-scale controller for research and development in cell culture and microbiology
- Fermentation of bacteria, yeasts, and fungi
- Cultivation of mammalian, insect, and human cell lines
- Cultivation of stem cells
Features
- Customizable and flexible thanks to the innovative bay-drawer concept for further extension and reconfiguration
- Integrated digital sensor technology (Mettler Toledo® ISM® and Hamilton ARC®), supporting analog sensors for pH and DO and optical DO sensors
- Optional PreSens® optical DO sensor technology for BioBLU Single-Use Bioreactors
- Variable speed pumps for accurate liquid addition and operation in batch and fed-batch mode
- Wide range TMFC to allow for individual mixing of air, N2, O2, and CO2 to headspace and/or submerged aeration
- Individual or parallel operation of two glass and/or BioBLU Single-Use Bioreactors, in any combination of bioreactor types
- Compact design, 16-40 cm of benchspace needed per vessel
- Cable management guides for a clean and tidy setup
- Temperature control block for advanced and user-friendly temperature control or temperature control via heat blankets and cooling fingers (benchtop bioreactors)
- Compatible with DASware® control software and BioNsight® cloud software
- Compatible with Bioprocess Autosampler
